Indole thromboxane synthetase inhibitors

Details Indole thromboxane synthetase inhibitors Indole thromboxane synthetase inhibitors

1981-12-03

1982-12-14

Jiles, Henry R.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D40106

Patent

active

043639127

ABSTRACT:
A series of novel 3-(pyrid-3- or -4-ylalkyl)-indoles useful as inhibitors of the action of the thromboxane synthetase enzyme without significantly inhibiting the action of the prostacyclin synthetase or cyclo- oxygenase enzymes is disclosed.

REFERENCES:
patent: 4322533 (1982-03-01), Lesher et al.
Ciba Ltd., Chem. Abstracts, vol. 65, 12175h, (1966).
Eur. J. Med. Chem.-Chimica Therapeutica, May-Jun. 1975, vol. 10, No. 3, pp. 276-285-English Summary.

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