Indole sPLA2 inhibitors

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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C548S491000

Reexamination Certificate

active

07026348

ABSTRACT:
A class of novel acylsulfonamide substituted indole compounds is disclosed together with the use of such compounds for inhibiting sPLA2mediated release of fatty acids for treatment of inflammatory diseases such as septic shock.

REFERENCES:
patent: 5578634 (1996-11-01), Bach et al.
patent: 5641800 (1997-06-01), Bach et al.
patent: 5654326 (1997-08-01), Bach et al.
patent: 5684034 (1997-11-01), Bach et al.
patent: 6451839 (2002-09-01), Bach et al.
patent: 6608099 (2003-08-01), Mihelich et al.

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