Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1996-07-02
1997-08-05
Richter, Johann
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
544295, 544362, C07D40114, A61K 31495
Patent
active
056543050
ABSTRACT:
The present invention provides compounds of formula ##STR1## wherein Y is >C.dbd.O or >S(O).sub.t wherein t is 1 or 2 and the pharmaceutically acceptable salts thereof which are potent antagonists of PAF and are useful in the treatment of PAF-related disorders including asthma, rhinitis, shock, respiratory distress syndrome, acute inflammation, transplanted organ rejection, gastrointestinal ulceration, allergic skin diseases, delayed cellular immunity, parturition, fetal lung maturation, and cellular differentiation.
REFERENCES:
patent: 5180723 (1993-01-01), Whittaker et al.
patent: 5180724 (1993-01-01), Bowles et al.
Carrera, Jr. George M.
Davidsen Steven K.
Sheppard George S.
Summers James B.
Abbott Laboratories
Browder Monte R.
Martin Michael B.
Myers, Jr. Richard S.
Richter Johann
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