Indole inhibitors of MDM2 and the uses thereof

Details Indole inhibitors of MDM2 and the uses thereof Indole inhibitors of MDM2 and the uses thereof

2007-08-30

2010-06-15

Chu, Yong (Department: 1626)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C548S486000

Reexamination Certificate

active

07737174

ABSTRACT:
The invention relates to small molecules which function as inhibitors of the interaction between p53 and MDM2. The invention also relates to the use of these compounds for inhibiting cell growth, inducing cell death, inducing cell cycle arrest and/or sensitizing cells to additional agent(s).

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