Indole fused heterocyclic diuretic compounds

Details Indole fused heterocyclic diuretic compounds Indole fused heterocyclic diuretic compounds

1972-08-10

1976-03-09

Coughlan, Jr., Paul M.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

2603269, 424274, C07D20912, C07D20914

Patent

active

039431487

ABSTRACT:
Substituted 1,2,4,5,6,7,8,9-octahydro-3H-azecino[5,4-b]-indoles and substituted 1,2,3,4,5,6,7,8-octahydroazonino[5,4-b]-indoles are prepared by cleavage of the corresponding quaternary alkyl iodide salts with lithium in liquid ammonia. The products possess diuretic activity.

REFERENCES:
patent: 3478051 (1969-11-01), Houlihan et al.
Wenkurt et al., Can. J. Chem. Vol. 42, pp. 489-490 (1964).
Herbst et al., J. Med. Chem. Vol. 9, pp. 864-868 (1966).

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