Indole derivatives as steroid 5.alpha.-reductase inhibitors

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514414, A61K 3141, A61K 3140

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active

059227478

ABSTRACT:
A method of treatment of a human to inhibit a steroid 5.alpha.-reductase, particularly a testosterone 5.alpha.-reductase, which comprises treating said human with an effective amount of a compound of the formula (I) ##STR1## or a pharmaceutically acceptable base salt thereof, wherein R is --CO.sub.2 H or tetrazol-5-yl;

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