Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2007-10-30
2007-10-30
Powers, Fiona T (Department: 1626)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C514S415000, C546S277400, C548S454000, C548S494000, C548S495000, C548S505000, C548S506000, C548S507000, C548S509000
Reexamination Certificate
active
11096673
ABSTRACT:
The present invention is directed to novel indole derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by the androgen receptor.
REFERENCES:
patent: 3452052 (1969-06-01), Binon et al.
patent: 3859279 (1975-01-01), Fothergill et al.
patent: 4341793 (1982-07-01), Ferris
patent: 6063810 (2000-05-01), Philippo et al.
patent: 6160109 (2000-12-01), Just et al.
patent: 2002/0169163 (2002-11-01), Hebeisen et al.
patent: 2004/0023999 (2004-02-01), Bekkali et al.
patent: 2005/0245485 (2005-11-01), Lanter et al.
patent: 663926 (1965-11-01), None
patent: 1123974 (1968-08-01), None
Gribble et al., J. Org. Chem., 49, 4518-4523, 1984.
Saulnier et al., J. Org. Chem., 47(5), 757-761, 1982.
Shinohara et al., Tetrahedron Letters, 43, 6937-6940, 2002.
Ziegler et al., J. Org. Chem., 36(13), 1759-1764, 1971.
Bahadur et al., Chemical Abstracts, 92:58533, 1980.
Gross et al., Chemical Abstracts, 95:23939, 1981.
Kost et al., Chemical Abstracts, 80:133171, 1974.
Maki et al., Chemical Abstracts, 109:149276, 1988.
Kost et al., Chemical Abstracts, 80:133171, 1974.
International Search Report for International Application No. PCT/US2005/011062 dated Aug. 24, 2005.
Basaria, S. et al.: Clinical Review 138: Anabolic-Androgenic Steroid Therapy in the Treatment of Chronic Diseases; the J Clin Endocrinology & Metabolism 86(11) pp. 5108-5117.
Chacun-Lefevre, L. et al.: Ring closure metathesis of indole 2-carboxylic acid allylamide derivatives; Tetrahedron 58 (2002) pp. 10181-10188.
Morris, Jeffrey J, et al. “Non-Sterodial Antiandrogens. Design of Novel Compounds Based on an Infrared Study of the Dominant Conformation and Hydrogen-Bonding Properties of a Series of Anilide Antiandrogens”. Journal of Medicinal Chemistry, vol. 31, No. 1, 1991, pp. 447-455. XP002341814.
Netchitailo, P. et al.: Synthese de flavones et de xanthones dans la serie du benzo[4,5]thiophene; J. Heterocyclic Chem., 15, (1978) pp. 337-342. (English-language summary only).
Newling, D.W.W.: Anti-androgens in the treatment of prostate cancer; British J. of Urology (1996) 77, pp. 776-784.
Shahidi, N.T. MD.: a Review of the Chemistry, Bioilogical Action, and Clinical Applications of Anabolic-Androgenic Steroids; Clinical Therapeutics, vol. 23, No. 9. (2001) pp. 1355-1390.
Wells, G. et al.: 4-Substituted 4-Hydroxycyclohexa-2,5-dien-1-ones with Selective Activities against Colon and Renal Cancer Cell Lines; J. Med. Chem. (2003) 46, pp. 532-541.
Fiordeliso James J.
Jiang Weiqin
Lanter James C.
Sui Zhihua
Zhang Xuqing
Janssen Pharmaceutica N.V.
Powers Fiona T
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