Indole derivatives as NMDA antagonists

Details Indole derivatives as NMDA antagonists Indole derivatives as NMDA antagonists

1998-05-29

1999-10-05

McKane, Joseph K.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514253, 514323, 514380, 514386, 514414, A61K 31415, C07D23104

Patent

active

059624965

ABSTRACT:
This invention relates to compounds of formula ##STR1## or a salt, or metabolically labile ester thereof wherein R represents a group selected from halogen, alkyl, alkoxy, amino, alkylamino, dialkylamino, hydroxy, trifluoromethyl, trifluoromethoxy, nitro, cyano, SO.sub.2 R.sub.2 or COR.sub.2 wherein R.sub.2 represents hydroxy, methoxy, amino, alkylamino, or dialkylamino; m is zero or an integer 1 or 2;

REFERENCES:
patent: 5145845 (1992-09-01), Johnson et al.
patent: 5256673 (1993-10-01), Bottcher et al.
patent: 5334606 (1994-08-01), Macleod
patent: 5418237 (1995-05-01), Bottcher et al.
patent: 5532241 (1996-07-01), Bottcher et al.

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