Indole derivatives as anti-inflammatory agents

Details Indole derivatives as anti-inflammatory agents Indole derivatives as anti-inflammatory agents

2006-07-11

2006-07-11

Saeed, Kamal A. (Department: 1626)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

active

07074939

ABSTRACT:
This invention relates to compounds, which are generally anti-inflammatory and analgesic compounds, and which are represented by Formula I:wherein A is a —CH2—, —O—, —S—, or —S(O)—; and the other substituents are as defined in the specification; or individual isomers, mixtures of isomers, and pharmaceutically acceptable salts thereof. The invention further relates to pharmaceutical compositions containing such compounds and methods for their use as therapeutic agents

REFERENCES:
patent: 4654360 (1987-03-01), Greenhouse et al.
patent: 6706662 (2004-03-01), Morgenstern et al.
patent: 4338770 (1995-05-01), None
patent: 396124 (1990-11-01), None
patent: WO 98/08818 (1998-03-01), None
patent: WO 99/43672 (1999-09-01), None
“The Canadian Study of Health and Aging: risk factors for Alzheimer's disease in Canada”,Neurology, (Nov. 1994) 44, 2073-2080.
Ara, G., et al, “Cycloxygenzase and lipoxygenase inhibitors in cancer therapy”,Prostaglindins, Leukotrienes and Essential Fatty Acids, (1996) No. 54, 3-16.
Breitner, John C.S., et al, “Delayed Onset of Alzheimer's Disease With Nonsteroidal Anti-Inflammatory and Histamine H2 Blocking Drugs”,Neurobiology of Aging, (1995) 16, No. 4, 523-530.
Eberhart, Charles E., et al, “Up-regulation of Cyclooxygenase 2 Gene Expression in Human Colorectal Adenomas and Adenocarinomas”,Gastroenterology(1994) No. 107, 1183-1188.
Instel, Paul A., “Analgesic-Antipyretic and Antiinflammatory Agents and Drugs Employed in the Treatment of Gout”,The Pharmaceutical Basis of Therapeutics, Ninth Edition, McGraw Hill, New York, 196, Chapter 27, 617-657.
Rogers, J., et al, “Clinical trial of indomethacin in Alzheimer's disease”,Neurology, (1993) 43, 1609-1611.

Affiliated with

Also associated with

Rating

Indole derivatives as anti-inflammatory agents does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Indole derivatives as anti-inflammatory agents, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Indole derivatives as anti-inflammatory agents will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3582686