Indole derivatives and therapeutically acting drugs

Details Indole derivatives and therapeutically acting drugs Indole derivatives and therapeutically acting drugs

1978-09-27

1980-04-29

Raymond, Richard

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

546 66, A61K 3144, D07D47104

Patent

active

042006384

ABSTRACT:
The invention relates to new indole derivatives, their preparation and use as drugs.
Said compounds may be represented by the general formula ##STR1## in which R represents a hydrogen atom or an alkyl or benzyl group and Z represents a hydrogen atom or a halogen atom or an alkyl, hydroxy, acyloxy, carbamate or methoxy group.
They are prepared by reacting tryptamine derivatives with synthons of the formula ##STR2## in which X and Y each represent an oxygen or sulphur atom, and R.sub.1 and R.sub.2 each represent an alkyl or phenyl radical or form together an alkylidene chain.
They may be used as intermediate compounds for chemical syntheses and also as drug for treating cerebro-vascular and cardio-circulatory insufficiencies.

REFERENCES:
Pinar et al., Chemical Abstracts, vol. 80 (1974) 60060f.

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