Indole derivatives and their use for testosterone 5-alpha-reduct

Details Indole derivatives and their use for testosterone 5-alpha-reduct Indole derivatives and their use for testosterone 5-alpha-reduct

1991-09-11

1993-05-18

Springer, David B.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

548492, 548469, 548494, 514418, C07D20918, C07D20920, A61K 31405, A61K 3141

Patent

active

052123200

ABSTRACT:
Indole derivatives of the formula ##STR1## and pharmaceutical compositions thereof. They are useful for treating or preventing testosterone 5-alpha-reductase-mediated diseases, such as alopecia, acnes and prostatism.

REFERENCES:
patent: 3699123 (1972-10-01), Seeman et al.
patent: 4060626 (1977-11-01), Hrstka et al.
patent: 4997845 (1991-03-01), Flaugh
patent: 5081145 (1992-01-01), Guindon et al.

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