Indole derivatives and their metal conjugates and uses thereof

Details Indole derivatives and their metal conjugates and uses thereof Indole derivatives and their metal conjugates and uses thereof

2007-08-10

2010-08-24

Saeed, Kamal A (Department: 1626)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C548S483000

Reexamination Certificate

active

07781480

ABSTRACT:
Provided are compounds which are indole derivatives, as well as pharmaceutical compositions containing the compounds. Also provided are methods of using the indole compounds for preventing or treating a disease, or a condition that predisposes to a disease, wherein the disease or condition is associated with activation of the serine/threonine kinase B (Akt) in an animal. The method comprises administering to the animal a preventive or treatment effective amount of the indole compound. Further provided is a method for increasing apoptosis of an animal cell comprising contacting the cell with the indole compound.

REFERENCES:
patent: WO 00/04903 (2000-02-01), None
“Cancer.” National Cancer Institute Online. Retrieved via Internet [Aug. 16, 2008] URL: http://www.cancer.gov/cancertopics/druginfo/alphalist.
Shimazaki, Yuichi. Metal Complexes involving indole rings: Structures and effects of metal-indole interactions. Coordination Chemistry Reviews. 253 (2009) 479-492.

Affiliated with

Also associated with

Rating

Indole derivatives and their metal conjugates and uses thereof does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Indole derivatives and their metal conjugates and uses thereof, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Indole derivatives and their metal conjugates and uses thereof will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-4150597