Indole derivatives and pharmaceutical use thereof

Details Indole derivatives and pharmaceutical use thereof Indole derivatives and pharmaceutical use thereof

1993-04-15

1994-12-20

Springer, David B.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

548492, 548181, 548235, 5483121, 546273, 544333, 514269, 5142372, 514256, 514365, 514375, 514393, C07D20918, C07D40512, A61K 31405, A61K 3138

Patent

active

053746481

ABSTRACT:
The invention relates to compounds of formula (I). ##STR1## or a salt, or metabolically labile ester thereof wherein R represents a group selected from halogen, alkyl, alkoxy, amino, alkylamino, dialkylamino, hydroxy, trifluoromethyl, trifluoromethoxy, nitro, cyano, SO.sub.2 R.sub.1 or COR.sub.1 wherein R.sub.1 represents hydroxy, methoxy, or amino; m is zero or an integer 1 or 2;

REFERENCES:
patent: 3010971 (1961-11-01), Kaiser et al.
patent: 4960786 (1990-10-01), Salituro et al.
patent: 5043334 (1991-08-01), Bell et al.
patent: 5145845 (1992-09-01), Johnson et al.
patent: 5284862 (1994-02-01), Bigge et al.
Salituro et al., J. Med. Chem., 1992, 35, 1791-1799.
Rowley et al., Bioorganic & Medicinal Chemistry Letters, 1992, 2(12), 1627-1630.
Salituro et al., J. Med. Chem., 1990, 33, 2946-2948.
Gray et al., J. Med. Chem., 1991, 34, 1283-1292.

Affiliated with

Also associated with

Rating

Indole derivatives and pharmaceutical use thereof does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Indole derivatives and pharmaceutical use thereof, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Indole derivatives and pharmaceutical use thereof will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2386416