Indole derivatives

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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Details

C544S105000, C548S454000, C548S465000, C548S491000

Reexamination Certificate

active

07135495

ABSTRACT:
Compounds represented by formula (I)wherein all symbols represent the same meanings as described in specification. and salts thereof.Since the compound represented by the formula (I) binds and antagonizes to DP receptor, it is useful for the prevention or treatment against the disease such as allergic disorder, diseases accompanied with itching, secondary diseases generated by behaviors caused by itching, inflammation, chronic obstructive pulmonary disease, ischemic reperfusion disorder, pleuritis complicated by rheumatoid arthritis, cerebrovascular disease, and ulcerative colitis.

REFERENCES:
patent: 3285908 (1966-11-01), Shen
patent: 3336194 (1967-08-01), Shen
patent: 5436265 (1995-07-01), Black et al.
patent: 6743793 (2004-06-01), Torisu et al.
patent: 458642 (1991-11-01), None
patent: 997638 (1965-07-01), None
Moreland et al, Treatment of Rheumatoid Arthritis with a Recombinant Human Tumor Necrosis Factor Receptor (p75)-Fc Fusion Protein, The New England Journal of Medicine, vol. 337, No. 3, pp. 141-147, 1997.
Lo et al, Interleukin-1β Induction of c-fos and Collagenase Expression in Articular Chondrocytes: Involvement of Reactive Oxygen Species, Journal of Cellular Biochemistry, vol. 69, pp. 19-29, 1998.
Neff et al, NF-kB and the MAP kinases/AP-1 pathways are both involved in interleukin-6 and interleukin-8 expression in fibroblast-like synoviocytes stimulated by protein I/II, Cellular Microbiology, vol. 3, No. 10, pp. 703-712, 2001.
San-Bao Hwang, et al., “Effects of Nonsteroid Antiinflammatory Drugs on the Specific Binding of Platelet Activating Factor to Membrane Preparations of Rabbit Platelets,”Thrombosis Research, vol. 34, pp. 519-531, 1984.

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