Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1993-02-25
1994-06-21
Ivy, C. Warren
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514339, 546201, 546273, C07D40114, C07D40314, C07D40304, A61K 31445
Patent
active
053228510
ABSTRACT:
Specific 2- and 2,5-substituted indoles or 2,3-dihydroindole compounds of the following formula ##STR1## wherein, R is formula 1a ##STR2## and X, X', Ar, R.sup.1, n, U, Z, V and W are defined in the specification are provided, having long lasting serotonin activity with specific binding to 5-HT.sub.2 receptors of the central nervous system. These compounds are suitable for therapeutic treatment of CNS disorders, such as anxiety, depression, sleep disturbances, migraine, negative symptoms of schizophrenia, and Parkinson's disease.
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Andersen Kim
Boegesoe Klaus P.
Pedersen Henrik
Perregaard Jens K.
Chang Celia
H. Lundbeck A/S
Ivy C. Warren
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