Indole derivatives

Details Indole derivatives Indole derivatives

1996-07-15

1999-04-06

Richter, Johann

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514418, 5142352, 514323, 514339, 514397, 514399, 514253, 548469, 548486, 548490, 548491, 5483351, 5483411, 5483421, 546201, 5462774, 5462777, 544143, 544144, 544373, A61K 3140, C07D20912, C07D20914, C07D20930

Patent

active

058919023

ABSTRACT:
The present invention relates to indole derivatives represented by formula (I): ##STR1## wherein R.sup.1 and R.sup.2 independently represent hydrogen, lower alkyl, hydroxy, lower alkoxy, halogen, --O--(CH.sub.2).sub.n --OR.sup.5, or ##STR2## R.sup.3 represents hydrogen, lower alkyl, or ##STR3## R.sup.4 represents hydroxy, lower alkoxy, substituted or unsubstituted aryloxy, or --NR.sup.10 R.sup.11, and X represents CO or SO.sub.2, with the proviso that when R.sup.3 is hydrogen or lower alkyl, and X is CO, R.sup.4 is --NR.sup.10 R.sup.11, or pharmaceutically acceptable salts thereof.

REFERENCES:
patent: 5296499 (1994-03-01), Sohda et al.
patent: 5413997 (1995-05-01), Kinoshita et al.
J. Med. Chem., vol. 17, No. 12 (1974) 1298-1304.

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