Indole derivative having PGD2 receptor antagonist activity

Details Indole derivative having PGD2 receptor antagonist activity Indole derivative having PGD2 receptor antagonist activity

2011-06-07

2011-06-07

Chu, Yong (Department: 1626)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C514S415000, C514S339000, C514S323000, C514S444000, C514S461000, C544S373000, C546S200000, C546S276700, C548S469000, C548S517000, C548S518000, C549S472000

Reexamination Certificate

active

07956082

ABSTRACT:
The present invention creates an indole derivative having DP receptor antagonistic activity and a pharmaceutical composition comprising the said compound as an active ingredient, and further a therapeutic agent for treating allergic diseases.A compound of the generic formula (I)wherein the ring A is an aromatic carbocyclic ring etc.; the ring B is a 3- to 8-membered nitrogen-containing non-aromatic heterocyclic ring etc.; R1, R2, R3, R4and R5are independently a hydrogen atom or a halogen atom etc.; R6is C2-C4 alkyloxy etc.; R7is independently a halogen atom etc.; R8is independently C1-C4 alkyl etc.; R9is carboxy etc.; Y is a single bond etc.; M is sulfonyl etc.; L1, L2and L3are a single bond or alkylene optionally containing one or two heteroatoms etc.; n is 0 etc.; q is 0 etc.;a pharmaceutically acceptable salt or hydrate thereof.

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