Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Patent
1998-03-06
2000-04-25
Richter, Johann
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
C07F 924
Patent
active
060545879
ABSTRACT:
Novel indole and azaindole compounds of the following structure and their use as fructose-1,6-bisphosphatase inhibitors is described: ##STR1## and pharmaceutically acceptable prodrugs and salts thereof.
REFERENCES:
patent: 3931206 (1976-01-01), Bowler et al.
patent: 4000305 (1976-12-01), Bowler et al.
patent: 4968790 (1990-11-01), DeVries et al.
patent: 5395826 (1995-03-01), Naumann et al.
patent: 5498617 (1996-03-01), Naumann et al.
patent: 5658889 (1997-08-01), Gruber et al.
patent: 5661174 (1997-08-01), Naumann et al.
Garuti, R., Synthesis and Biological Evaluation of Some New Phosphonates, Pharmazie, 47, Dec. 1992.
Yoshino et al., "Organic phosphorus compounds. 2. Synthesis and coronary vasodilator activity of (Benzothiazolylbenzyl) phosphonate derivatives," J. Med. Chem. 32:1528-1532 (1989).
McNeil et al., J. Med. Chem. 106:7851 (1984).
Patent Abstracts of Japan, 17(442) (C-1097), Aug. 16, 1993 & JP 05 097883 A.
Shoji, et al., "Preparation of imidazo[1,2-a]pyridine derivatives as antihyperlipidemics and ischemia-reperfusion injury improvers and their intermediates as alpha-haloketone derivatives", Chemical Abstracts 118(5), Feb. 1, 1993.
Dang Qun
Erion Mark D.
Kasibhatla Srinivas Rao
Reddy K. Raja
Reddy M. Rami
Keating Dominic
Metabasis Therapeutics, Inc.
Richter Johann
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