Indole amide derivatives as EP4 receptor antagonists

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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C514S379000, C514S394000, C514S406000, C514S415000, C514S416000, C548S207000, C548S241000, C548S261000, C548S304400, C548S362500, C548S494000

Reexamination Certificate

active

07968578

ABSTRACT:
The invention is directed to indole amide derivatives as EP4 receptor antagonists useful for the treatment of EP4 mediated diseases or conditions, such as acute and chronic pain, osteoarthritis, rheumatoid arthritis and cancer. Pharmaceutical compositions and methods of use are also included.

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