Indole acetic acids exhibiting CRTH2 receptor antagonism and...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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Details

C548S458000

Reexamination Certificate

active

07601749

ABSTRACT:
The invention relates to indole acetic acid compounds which function as antagonists of the CRTH2 receptor. The invention also relates to the use of these compounds to inhibit the binding of prostaglandin D2and its metabolites or certain thromboxane metabolites to the CRTH2 receptor and to treat disorders responsive to such inhibition.

REFERENCES:
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patent: 6114532 (2000-09-01), Ries et al.
patent: 6121308 (2000-09-01), Hauel et al.
patent: WO 02/060438 (2002-08-01), None
patent: WO 03/066046 (2003-08-01), None
patent: WO 03/066047 (2003-08-01), None
patent: WO 03/101961 (2003-12-01), None
patent: WO 03/101981 (2003-12-01), None
patent: WO 2004/007451 (2004-01-01), None
International Search Report for corresponding PCT Application No. PCT/US2005/034029 dated Apr. 27, 2007.
International Search Report for PCT Application No. PCT/US2005/034028 dated Mar. 23, 2006.
Office Action issued in parent U.S. Appl. No. 11/230,917, mailed on Nov. 9, 2007.
Office Action issued in parent U.S. Appl. No. 11/230,917, mailed on Jul. 20, 2007.

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