Indole 3-carboxylic acid derivatives

Details Indole 3-carboxylic acid derivatives Indole 3-carboxylic acid derivatives

1993-04-01

1994-09-06

Springer, David B.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

548493, C07D20942

Patent

active

053449380

ABSTRACT:
An indole derivative represented by formula (I): ##STR1## wherein R.sup.1 is a lower alkoxymethyl group or a formyl group, R.sup.2 is a lower alkyl group, R.sup.3 is a hydrogen atom or a lower alkyl group and R.sup.4 is a hydrogen atom or a lower alkyl group, which is useful as an intermediate for the synthesis of a compound, 5-aziridino-3-hydroxymethyl-l-methyl-2- (1H-indole-4,7-dione)prop-.beta.-ene-.alpha.-ol, which has antitumor activity.

REFERENCES:
J. Prakt Chem., 311 (5), 807 (1969).
Chemical Abstract, vol. 9, 2868n (1968).
Chemical Abstract, vol. 70, 47295K (1969).
Chemical Abstract, vol. 109, 92188n (1988).
Chemical Abstract, vol. 115, 135866a (1991).

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