Indole-3-carboxylic acid amide, ester, thioamide and thiol...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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C548S492000

Reexamination Certificate

active

07737173

ABSTRACT:
The invention provides compounds represented by the formula I, each of which compounds may have sphingosine-1-phosphate receptor agonist and or antagonist biological activity:and wherein the variables Y, R4, n, A, X, Z, R1, o, R3, R2and p are as defined in the specification. These compounds are useful for treating a disease or condition selected from the group consisting of glaucoma, dry eye, angiogenesis, cardiovascular conditions and diseases, and wound healing.

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