Surgery – Diagnostic testing – Detecting nuclear – electromagnetic – or ultrasonic radiation
Reexamination Certificate
2005-09-13
2005-09-13
Shaw, Shawna J. (Department: 3737)
Surgery
Diagnostic testing
Detecting nuclear, electromagnetic, or ultrasonic radiation
C600S473000, C424S009600, C607S089000
Reexamination Certificate
active
06944493
ABSTRACT:
Aqueous indocyanine green (ICG) composition exhibiting enhanced stability, as well as enhanced ICG concentration, as compared to presently available ICG products. The composition comprises an aqueous ICG composition comprising ICG at a concentration of at least about 10 mg/ml and an aqueous diluent, wherein the composition is stable for at least 24 hours. Diagnostic and therapeutic methods for using these aqueous compositions are also contemplated, e.g., angiography, dye-enhanced photocoagulation, photodynamic therapy, for a variety of conditions, including Age-Related Macular Degeneration (ARMD), lesions and tumors.
REFERENCES:
patent: 1048419 (1912-12-01), Krumbiegel et al.
patent: 2895955 (1959-07-01), Heseltine et al.
patent: 3736524 (1973-05-01), Drexhage
patent: 3871772 (1975-03-01), Munnerlyn et al.
patent: 3893447 (1975-07-01), Hochheimer et al.
patent: 3944341 (1976-03-01), Pomerantzeff
patent: 4056310 (1977-11-01), Shimizu et al.
patent: 4251139 (1981-02-01), Matsumura
patent: 4369250 (1983-01-01), Gindler
patent: 4412543 (1983-11-01), Vassiliadis et al.
patent: 4466442 (1984-08-01), Hilmann et al.
patent: 4541438 (1985-09-01), Parker et al.
patent: 4573778 (1986-03-01), Shapiro
patent: 4608990 (1986-09-01), Elings
patent: 4762701 (1988-08-01), Horan et al.
patent: 4786813 (1988-11-01), Svanberg et al.
patent: 4799783 (1989-01-01), Takahashi et al.
patent: 4821117 (1989-04-01), Sekiguchi
patent: 4835103 (1989-05-01), Cercek et al.
patent: 4842401 (1989-06-01), Maurice
patent: 4859584 (1989-08-01), Horan et al.
patent: 4978213 (1990-12-01), El Hage
patent: 5072731 (1991-12-01), Taratuta et al.
patent: 5092331 (1992-03-01), Nakamura et al.
patent: 5116114 (1992-05-01), Nakamura et al.
patent: 5126235 (1992-06-01), Hioki
patent: 5141303 (1992-08-01), Yamamoto et al.
patent: 5150292 (1992-09-01), Hoffmann et al.
patent: 5163437 (1992-11-01), Fujii et al.
patent: 5225859 (1993-07-01), Fleischman
patent: 5247318 (1993-09-01), Suzuki
patent: 5277913 (1994-01-01), Thompson et al.
patent: 5279298 (1994-01-01), Flower
patent: 5292362 (1994-03-01), Bass et al.
patent: 5303709 (1994-04-01), Dreher et al.
patent: 5315998 (1994-05-01), Tachibana et al.
patent: 5394199 (1995-02-01), Flower
patent: 5400791 (1995-03-01), Schlier et al.
patent: 5438989 (1995-08-01), Haglund et al.
patent: 5441858 (1995-08-01), Delprato et al.
patent: 5450144 (1995-09-01), Ben Nun
patent: 5552452 (1996-09-01), Khadem et al.
patent: 5569587 (1996-10-01), Waggoner et al.
patent: 5573750 (1996-11-01), Singh
patent: 5576013 (1996-11-01), Williams et al.
patent: 5618733 (1997-04-01), Sakata et al.
patent: 5624597 (1997-04-01), Buhl et al.
patent: 5643356 (1997-07-01), Nohr et al.
patent: 5648062 (1997-07-01), Klaveness et al.
patent: 5676928 (1997-10-01), Klaveness et al.
patent: 5691204 (1997-11-01), Kantor et al.
patent: 5707608 (1998-01-01), Liu
patent: 5707986 (1998-01-01), Miller et al.
patent: 5716642 (1998-02-01), Bagchi et al.
patent: 5719027 (1998-02-01), Miyazaki et al.
patent: 5747475 (1998-05-01), Nordquist et al.
patent: 5750722 (1998-05-01), Huynh et al.
patent: 5762957 (1998-06-01), Mehlhorn
patent: 5773299 (1998-06-01), Kim et al.
patent: 5798349 (1998-08-01), Levy et al.
patent: 5804448 (1998-09-01), Wang et al.
patent: 6248727 (2001-06-01), Zeimer
patent: 6351663 (2002-02-01), Flower et al.
patent: 6443976 (2002-09-01), Flower et al.
patent: 2002/0028474 (2002-03-01), Shibamura et al.
patent: 2004/0156782 (2004-08-01), Alam et al.
patent: 3124305 (1983-01-01), None
patent: 244492 (1987-04-01), None
patent: 3926652 (1991-04-01), None
patent: 0109846 (1984-05-01), None
patent: 0554643 (1993-08-01), None
patent: 0649667 (1995-04-01), None
patent: 0791361 (1997-08-01), None
patent: 589825 (1998-05-01), None
patent: 2034916 (1980-06-01), None
patent: 87042892 (1987-09-01), None
patent: 95/24930 (1995-09-01), None
patent: 96/31237 (1996-12-01), None
patent: 97/31582 (1997-09-01), None
patent: 97/33620 (1997-09-01), None
patent: 97/46262 (1997-12-01), None
patent: 00/41726 (2000-07-01), None
Maarek et al. “Fluorescence of indocyanine green in blood: intensity dependence on concentration and stabilization with sodium polyaspartate,” Journal of Photochemistry and Photobiology B: Biology 65 (2001) 157-164.
“Photosensitizer,”Ophthamalmic Surgery and Lasers,vol. 28, No. 5, p 410 (1997).
Desmettre et al., “Diode Laser-Induced Thermal Damage Evaluation on the Retina with a Liposome Dye System,”Lasers in Surgery and Medicine,vol. 24, pp. 61-68 (1999).
Flower et al., “Evolution of Indocyanine Green Dye Choroidal Angiography,”Optical Engineering,vol. 34, No. 3, pp. 727-736 (1995).
Flower et al., “Pulsatile Flow in the Choroidal Circulation: A Preliminary Investigation,”Eye,vol. 4, pp. 310-318 (1990).
Flower et al., “Variability in Choriocapillaris Blood Flow Distribution,”Investigative Ophthalmology&Visual Science,vol. 36, No. 7, pp. 1247-1258 (1995).
Flower, “Choroidal Angiography Today and Tomorrow,”Retina,vol. 12, No. 3, pp. 189-190 (1992).
Flower, “Extraction of Choriocapillaris Hemodynamic Data from ICG Fluorescence Angiograms,”Investigative Ophthalmology&Visual Science,vol. 34, No. 9, pp. 2720-2729 (1993).
Flower, “Injection Technique for Indocyanine Green and Sodium Fluorescein Dye Angiography of the Eye,”Investigative Ophthalmology,vol. 12, No. 12, pp. 881-895 (1973).
Gathje et al., “Stability Studies on Indocyanine Green Dye,”Journal of Applied Physiology,vol. 29, No. 2 pp. 181-185 (1970).
Holzer et al., “Photostability and Thermal Stability of Indocyanine Green,”J. Photochem. Photobiol. B: Biol.vol. 47, pp. 155-164 (1998).
Klein et al., “An Image Processing Approach to Characterizing Choroidal Blood Flow,”Investigative Ophthalmology&Visual Science,vol. 31, No. 4, pp. 629-637 (1990).
Miki et al., “Computer Assisted Image Analysis Using the Subtraction Method in Indocyanine Green Angiography,”European Journal of Ophthalmology,vol. 6, No. 1, pp. 30-38 (1996).
DuBosar, “Population at Risk: Age-Related Macular Degeneration,”Ocular Surgery News,10 Pages, (May 15, 1998).
Chen et al., “Photothermal Effects on Murine Mammary Tumors Using Indocyanine Green and an 808-nm Diode Laser: an in vivo Efficacy Study,”Cancer Lett.,vol. 98, No. 2, pp. 169-173 (1996).
Alcon Pharmaceuticals Ltd. “Pharmacyclics Inc,”The Business and Medicine Report,p. 63 (Jan. 1998).
Shiraga et al., “Feeder Vessel Photocoagulation of Subfoveal Choroidal Neovascularization Secondary to Age-Related Macular Degeneration,”Ophthalmology,vol. 105, No. 4, pp. 662-669 (1998).
Flower et al., “Clinical Infrared Absorption Angiography of the Choroid,”American Journal of Ophthalmology,vol. 73, No. 3, pp. 458-459 (1972).
Flower et al., “A Clinical Technique and Apparatus for Simultaneous Angiography of the Separate Retinal and Choroidal Circulation,” Investigative Ophthalmology, vol. 12(4), pp. 248-261 (1973).
Hochheimer et al., “Angiography of the Cervix,”John Hopkins Medical Journal,vol. 135, pp. 375-382 (1974).
Flower, “High Speed Human Choroidal Angiography Using Indocyanine Green Dye and a Continuous Light Source,”International Symposium on Fluorescein Angiography, Documenta OphthmologicaProceedings Series, vol. 9, pp. 59-64 (1976).
Flower et al., “Indocyanine Green Dye Fluorescence and Infrared Absorption Choroidal Angiography Performed Simultaneously with Fluorescein Angiography,”Johns Hopkins Medical Journal,vol. 138, No. 2 pp. 33-42 (1976).
Orth et al., “Potential Clinical Applications of Indocyanine Green Choroidal Angiography,”The Eye, Ear, Nose and Throat Monthly,vol. 55, Jan., pp. 15-28, 58 (1976).
Patz et al., “Clinical Applications of Indocyanine Green Angiography,”International Symposium on Fluorescein Angiography, Documents Ophthmologica,vol. 9 , pp.245-251 (1976).
Flower, “Choro
Alam Abu
Chavan Ashok J.
Flower Robert W.
Akora, Inc.
Leydig , Voit & Mayer, Ltd.
Shaw Shawna J.
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