Indium-111 oxine complex composition

Details Indium-111 oxine complex composition Indium-111 oxine complex composition

1980-03-10

1982-06-15

Nucker, Christine M.

Drug, bio-affecting and body treating compositions

Radionuclide or intended radionuclide containing; adjuvant...

Molecular bilayer structure

424 9, A61K 4900, A61K 4300

Patent

active

043350950

ABSTRACT:
An indium-111 preparation comprises a complex of indium-111 with a quinoline compound carrying an 8-hydroxyl group, e.g. oxine, present in an aqueous medium which also contains a surface active agent to prevent the complex from becoming bound to the surface of the vessel on autoclaving, and optionally a buffer to improve blood cell labelling efficiency. The surface active agent is preferably non-ionic, e.g. a polyoxyethylene sorbitan ester of a fatty acid. The buffer is preferably N-2-hydroxyethylpiperazine-N'-2-ethanesulphonic acid.

REFERENCES:
patent: 3728351 (1973-04-01), Counsell et al.
patent: 4017596 (1977-04-01), Loberg et al.
Merrick et al., from Medical Radioisotope Scintigraphy 1972, IAEA, Vienna, 1973, pp. 721-729.
Heindel et al., Ed., The Chemistry of Radio Pharmaceuticals, Masson Publishing USA, Inc, New York (1978), p. 43.
Thakur et al., Chemical Abstracts, vol. 87, 1977, Abstract #35098m.

Affiliated with

Also associated with

Rating

Indium-111 oxine complex composition does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Indium-111 oxine complex composition, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Indium-111 oxine complex composition will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1918982