Indicator for detecting residual ethylene oxide

Chemical apparatus and process disinfecting – deodorizing – preser – Analyzer – structured indicator – or manipulative laboratory... – Calorimeter

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422 57, 422 58, 422 87, 436 1, 436 93, G01N 3122

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active

046786406

ABSTRACT:
An indicator for detecting residual ethylene oxide comprising a substrate impregnated with a solution of 4-(4-nitrobenzyl)pyridine and an envelope of the substrate which is at least partially transparent and has low permeability to gaseous ethylene oxide is provided, the envelope being preferably made of a transparent plastic film. With the indicator, an amount of ethylene oxide remaining in various medical instruments, etc. may be estimated by the naked eye since the color of the indicator changes step by step in the course of the release of residual ethylene oxide.

REFERENCES:
patent: 2998306 (1961-08-01), Huyck et al.
patent: 3627469 (1971-12-01), Cheng
patent: 3738811 (1973-06-01), Cheng
patent: 3992154 (1976-11-01), Whitbowine et al.
patent: 4094642 (1978-06-01), Sumimoto et al.
patent: 4138216 (1979-02-01), Larson et al.
patent: 4195058 (1980-03-01), Patel
patent: 4436819 (1984-03-01), Manning
patent: 4495291 (1985-01-01), Lawton
Brewer, et al., "Biological-Chemical Indicator For Ethylene Oxide Sterilization"-Journal of Pharmaceutical Science, vol. 55, No. 1, pp. 57-59 (1961).

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