Indene derivatives and their use as PAF-antagonists

Details Indene derivatives and their use as PAF-antagonists Indene derivatives and their use as PAF-antagonists

1983-11-14

1987-04-07

Holrah, Glennon H.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Ester doai

514602, 514311, 514396, 514381, 560 10, 564 85, 548335, 548252, 546216, 544248, C07D25704

Patent

active

046561900

ABSTRACT:
Indene derivatives have been found to have potent and specific PAF (Platelet-Activating-Factor) antagonistic activities and are thereby useful in the treatment of various diseases or disorders mediated by the PAF, for example, inflammation, cardiovascular disorder, asthma, lung edema, and adult respiratory distress syndrome.

REFERENCES:
patent: 3654349 (1972-04-01), Shen et al.
patent: 3737455 (1973-06-01), Shen et al.
patent: 3822310 (1974-07-01), Shen et al.
patent: 3882239 (1975-06-01), Shen et al.
patent: 3932498 (1976-01-01), Shen et al.
patent: 4087549 (1978-02-01), Shen et al.

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