Indene compounds

Details Indene compounds Indene compounds

1986-07-11

1988-08-09

Hollrah, Glennon H.

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitrogen attached directly or indirectly to the purine ring...

540492, 544381, 544386, 544391, 546197, 546206, 548159, 549433, 564428, 564308, C07D40504

Patent

active

047629274

ABSTRACT:
The invention provides an indene compound represented by the following general formula (I): ##STR1## wherein R.sub.1 means a lower alkyl group, R.sub.2 and R.sub.3 denote a lower alkyl group individually or an alkylenedioxy group in combination, and R.sub.4 and R.sub.5 mean individually a substituted or unsubstituted lower alkyl or aryl group or in combination a substituted or unsubstituted piperidino, piperazinyl or homopiperazinyl group together with the adjacent nitrogen atom, with a proviso that not both R.sub.4 and R.sub.5 are a methyl group at the same time.

REFERENCES:
patent: 4082773 (1978-04-01), Hauck
patent: 4393226 (1983-07-01), Witiak et al.
Chemical Abstracts, vol. 90, No. 7, Feb. 12, 1979, Columbus, Ohio, U.S.A.; Witiak, D. R.; Baldwin, J. R.; Rahwan, R. G. "Pharmacology on ratileum of certain 2-substituted 3-(dimethylamino)-5,6-dimethoxy indenes related to 5,6-(methylendioxy) indene calcium antagonist" p. 21, col. 2, abstract No. 48 256y & J. hed. Chem. 1978, 21(12), 1313-15.

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