Indazolyl sulphonamide derivatives useful as glucocorticoid...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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C548S361100, C548S361500

Reexamination Certificate

active

08030340

ABSTRACT:
Compounds of formula (I):or a pharmaceutically acceptable salt thereof, compositions comprising them, processes for preparing them and their use in medical therapy (for example modulating the glucocorticoid receptor in a warm blooded animal).

REFERENCES:
patent: 3992441 (1976-11-01), Helland
patent: 4443477 (1984-04-01), Witte et al.
patent: 4948809 (1990-08-01), Witte et al.
patent: 5861401 (1999-01-01), Bradbury
patent: 6323199 (2001-11-01), Lehmann et al.
patent: 7297709 (2007-11-01), Dai et al.
patent: 2004/0235892 (2004-11-01), Dai et al.
patent: 2007/0265326 (2007-11-01), Biggadike et al.
patent: 2008/0207721 (2008-08-01), Berger et al.
patent: 2008/0214641 (2008-09-01), Berger et al.
patent: 2009/0093485 (2009-04-01), Bladh et al.
patent: 2009/0124607 (2009-05-01), Bladh et al.
patent: 2009/0170898 (2009-07-01), Bengtsson et al.
patent: 0031954 (1981-07-01), None
patent: 0201735 (1986-11-01), None
patent: 0261539 (1988-03-01), None
patent: 0558258 (1993-09-01), None
patent: 0569193 (1993-11-01), None
patent: 0610896 (1994-08-01), None
patent: 0679641 (1995-11-01), None
patent: 0947500 (1999-10-01), None
patent: 0976722 (2000-02-01), None
patent: 1190710 (2002-03-01), None
patent: 1447401 (2004-08-01), None
patent: 0607840.6 (2006-04-01), None
patent: WO95/02580 (1995-01-01), None
patent: WO95/03279 (1995-02-01), None
patent: WO95/33461 (1995-12-01), None
patent: WO96/06822 (1996-03-01), None
patent: WO96/36595 (1996-11-01), None
patent: WO99/33786 (1999-07-01), None
patent: WO99/38845 (1999-08-01), None
patent: WO01/24786 (2001-04-01), None
patent: WO01/46172 (2001-06-01), None
patent: WO02/20474 (2002-03-01), None
patent: WO02/28820 (2002-04-01), None
patent: WO03/028641 (2003-04-01), None
patent: WO03/076401 (2003-09-01), None
patent: WO03/086294 (2003-11-01), None
patent: WO03/099773 (2003-12-01), None
patent: WO2004/018414 (2004-03-01), None
patent: WO2004/019935 (2004-03-01), None
patent: WO2004/050631 (2004-06-01), None
patent: WO2004/073634 (2004-09-01), None
patent: WO2004/089913 (2004-10-01), None
patent: WO2004/110418 (2004-12-01), None
patent: WO2005/004810 (2005-01-01), None
patent: WO2005/060963 (2005-07-01), None
patent: WO2005/077895 (2005-08-01), None
patent: WO2005/086904 (2005-09-01), None
patent: WO2005/123688 (2005-12-01), None
patent: WO2006/046914 (2006-05-01), None
patent: WO2006/046916 (2006-05-01), None
patent: WO2006/135826 (2006-12-01), None
patent: WO2006/138373 (2006-12-01), None
patent: WO 2007/046747 (2007-04-01), None
patent: WO2007/054294 (2007-05-01), None
patent: WO2007/114763 (2007-10-01), None
patent: WO2007/122165 (2007-11-01), None
patent: WO2008/008882 (2008-01-01), None
patent: WO2008/043788 (2008-04-01), None
patent: WO2008/043789 (2008-04-01), None
patent: WO2008/051532 (2008-05-01), None
patent: WO2008/057856 (2008-05-01), None
patent: WO2008/057857 (2008-05-01), None
patent: WO2008/063116 (2008-05-01), None
patent: WO2008/070507 (2008-06-01), None
patent: WO2008/076048 (2008-06-01), None
patent: WO2008/079073 (2008-07-01), None
patent: WO2008/124665 (2008-10-01), None
patent: WO2008/124745 (2008-10-01), None
patent: WO2008/135578 (2008-11-01), None
patent: WO2009/050218 (2009-04-01), None
patent: WO2009/050220 (2009-04-01), None
patent: WO2009/050221 (2009-04-01), None
patent: WO2009/050243 (2009-04-01), None
patent: WO2009/050244 (2009-04-01), None
patent: WO2009/062950 (2009-05-01), None
patent: WO2009/074590 (2009-06-01), None
patent: WO2009/108525 (2009-09-01), None
patent: WO2009/111214 (2009-09-01), None
Bradbury et al., “New Non-Peptide Endothelin-A Receptor Antagonists: Synthesis, Biological Properties, and Structure-Activity Relationships of 5-(Dimethylamino)-N-pyridyl-, -N-pyrimidinyl-N-pyridazinyl-, and -N-pyrazinyl-1-naphthalenesulfonamides”,J. Med. Chem. 40:996-1004 (1997).
Fabiana et al., “Mode of Action of Sulfanilyl Fluoroquinolones”,Antimicrobial Agents and Chemotherapy42:1495-1498 (1998).
Gaedcke et al., “Structure dependence of antiplasmodic activity of 3-IN-(4′-amidosulphonylphenypamin˜methyl] quinoline”,Arch. Pharm(Weinheim) 313:166-173 (1930).
Jansen et al., “Hydantoin-Substituted 4,6-Dichloroindole-2-carboxylic Acids as Ligands with High Affinity for the Glycine Building Site of the NMDA Receptor”,J. Med. Chem. 46:64-73 (2003).
STN International file Registry: RN 321722-44-5, RN 321704-10-3, RN 321704-02-3, RN 321703-82-6, RN 321703-77-9, RN 321703-75-7.
STN International file Registry: RN 674768-65-1, RN 343372-84-9, RN 343372-70-3, RN 339016-98-7, RN 519018-69-0, RN 261623-54-5.
Clark et al., “1H-Pyrazolo[3,4-g]hexahydro-isoquinolines as selective glucocorticoid receptor antagonists with high functional activity”,Bioorg. Med. Chem. Lett. 18:1312-1317 (2008).
Mohler et al., “Dissociated non-steroidal glucocorticoids: tuning out untoward effects”,Expert Opin. Ther. Patents17:37-58 (2007).
Mohler et al., “Non-steroidal glucocorticoid receptor antagonists: the race to replace RU-486 for anti- glucocorticoid therapy”,Expert Opin. Ther. Patents17:59-81 (2007).
Schäcke et al., “Dissociated non-steroidal glucocorticoid receptor modulators: an update on new compounds”,Expert Opin. Ther. Patents18:339-352 (2008).
USPTO Notice of Allowance in U.S. Appl. No. 12/005,066, mailed Mar. 24, 2009, 10 pages.
Fish & Richardson P.C., Request for Continued Examination in U.S. Appl. No. 12/005,066, filed Jun. 19, 2009, 6 pages.
USPTO Notice of Allowance in U.S. Appl. No. 12/005,066, mailed Sep. 9, 2009, 6 pages.
Fish & Richardson P.C., Request for Continued Examination in U.S. Appl. No. 12/005,066, filed Nov. 10, 2009, 5 pages.
USPTO Notice of Allowance in U.S. Appl. No. 12/005,066, mailed Jan. 13, 2010, 8 pages.

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