Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1988-03-16
1989-12-12
Rotman, Alan L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514304, 546112, 546126, 548372, C07D40312, A61K 31415, A61K 31445
Patent
active
048868086
ABSTRACT:
Compounds of formula (I) and pharmaceutically acceptable salts thereof: ##STR1## wherein X is CO and Y is NH;
REFERENCES:
World Patents Index (Derwent) Accession No. 85-045742/08 (Feb. 1984).
P. Fludzinski et al., "Indazoles as Indole Bioisosteres: Synthesis and Evaluation of the Tropanyl Ester and Amide of Indazole-3-Carboxylate as Antagonists at the Serotonin 5HT.sub.3 Receptor", J. Medicinal Chem., 30(9), pp. 1535-1537 (1987).
"5HT.sub.3 -Antagonists in Anxiety and Szhizophrenia", SCRIP, No. 1264, Dec. 9, 1987, p. 23.
Barr David K.
Beecham Group p.l.c.
Evans Emily A.
Haley, Jr. James F.
Rotman Alan L.
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