Indazole derivatives, processes for making the same and pharmace

Details Indazole derivatives, processes for making the same and pharmace Indazole derivatives, processes for making the same and pharmace

1975-04-22

1976-08-31

Moyer, Donald B.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

2602955S, 260302H, 260310R, 260310C, 260311, 424273, C07D23156, C07D27724, C07D21318, C13K 1300

Patent

active

039780449

ABSTRACT:
This invention relates to indazole derivatives, to processes for their preparation and to pharmaceutical compositions containing them.
More specifically this invention relates to 4, 5, 6, 7-tetrahydroindazoles bearing at the 3-position an amino substituent.
This invention also relates to processes for producing the same which include the steps of condensing a substituted cyclohexanone with a secondary amine, reacting the thus formed enamine either with an isocyanate or thiocyanate or with phosgene imonium salt and cyclizing the intermediate compound with a hydrazino derivative.
The compounds of the invention have therapeutic utility, namely as a means for controlling fertility in mammals.

REFERENCES:
patent: 3133081 (1964-05-01), Lafferty et al.
patent: 3736332 (1973-05-01), Butula

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