Indazole derivatives

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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Details

C514S364000, C514S365000, C514S381000, C514S406000, C546S275700, C548S181000, C548S253000

Reexamination Certificate

active

08071628

ABSTRACT:
The invention is concerned with novel indazole derivatives of formula (I)wherein R1, R2, R3, R4, R5, R6, X and Y are as defined in the description and in the claims, as well as physiologically acceptable salts and esters thereof. These compounds inhibit L-CPT1 and can be used in the prevention or treatment of diseases which are modulated by L-CPT1 inhibitors.

REFERENCES:
patent: 2004/0110945 (2004-06-01), Nakayama et al.
patent: 102004054666 (2006-05-01), None
patent: 2005056532 (2005-06-01), None
Korbonits, E., et al., Journal of the Chemical Society, vol. 1, No. 3, pp. 759-766 (1981), XP002221091.
Sall et al., J. Med. Chem., 40, pp. 2843-2857 (1997).
Snyder et al., J. Am. Chem. Soc., 74, pp. 2009-2012 (1952).
Jackson et al., Biochem., 341, pp. 483-189 (1999).
Jackson et al., J. Biol. Chem., 275, pp. 19560-19566 (2000).

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