Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2007-06-19
2007-06-19
McKenzie, Thomas (Department: 1625)
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
active
11112423
ABSTRACT:
Indazole compounds that modulate and/or inhibit cell proliferation, such as the activity of protein kinases are described. These compounds and pharmaceutical compositions containing them are capable of mediating, e.g., kinases-dependent diseases to modulate and/or inhibit unwanted cell proliferation. The invention is also directed to the therapeutic or prophylactic use of pharmaceutical compositions containing such compounds, and to methods of treating cancer as well as other disease states associated with unwanted angiogenesis and/or cellular proliferation, such as diabetic retinopathy, neovascular glaucoma, rheumatoid arthritis, and psoriasis, by administering effective amounts of such compounds.
REFERENCES:
patent: 3862958 (1975-01-01), Ruechardt et al.
patent: 3994890 (1976-11-01), Fujimura et al.
patent: 4051145 (1977-09-01), Dupre et al.
patent: 4978603 (1990-12-01), Inoue et al.
patent: 5221601 (1993-06-01), Graindourze et al.
patent: 5612360 (1997-03-01), Boyd et al.
patent: 5621082 (1997-04-01), Xiong et al.
patent: 5733920 (1998-03-01), Mansuri et al.
patent: 5760028 (1998-06-01), Jadhav et al.
patent: 6020336 (2000-02-01), Lavielle et al.
patent: 6046205 (2000-04-01), Lavielle et al.
patent: 6919461 (2005-07-01), Reich et al.
patent: 2003/0105336 (2003-06-01), Schindler et al.
patent: 2004/0092546 (2004-05-01), Wei et al.
patent: WO02/010137 (2002-07-01), None
Greene, Theodora ,Protective Groups in Organic Synthesis,Third Edition, John Wiley & Sons, Inc.
Webster, Exp. Opin. Invest. Drugs, vol. 7 (1998), pp. 865-887.
Stover et al., Current Opinion in Drug Discovery and Development; vol. 2 (1999), pp. 274-285.
Sedlacek et al., Int. J. Oncol., vol. 9 (1996), pp. 1143-1168.
Schow et al., Bioorg. Med. Chem. Lett., vol. 7 (1997), pp. 2697-2702.
Legravend et al., Bioorg. Med. Chem. Lett., vol. 8 (1998), pp. 793-798.
Chang, et al., Chemistry & Biology, vol. 6 (1999), pp. 361-375.
Whitten et al., J. Org. Chem. 51, 1891 (1986).
Elpern et al., J. Amer. Chem. Soc., 68, 1946, 1436.
Weinreb et al., Tet. Lett. 27, 19, 1986, 2099-2102.
Gu, et al., Tet. Lett., 37, 15, 1996, 2565-2568.
Kwon et al., Synthesis, 1976, 249.
Harvey et al., J. Chem. Soc. Perk. Trans. 1, 1988, 1939-1944.
Daidone et al., Heterocycles (1996), 43(11), 2385-2396.
Hager et al., Acta Crystallogr., Sect. C: Cryst. Struct. Commun. (1996), 52(11), 2894-2896.
Kamel et al., Tetrahedron (1973), 29(1), 221-225.
Bleckman Ted Michael
Kephart Susan Elizabeth
Reich Siegfried Heinz
Romines, III William Henry
Wallace Michael Brennan
Agouron Pharmaceuticals , Inc.
Hua Ye
McKenzie Thomas
Prodnuk Stephen H.
Robinson Binta
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