Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2005-07-19
2005-07-19
Tsang, Cecilia J. (Department: 1625)
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
active
06919461
ABSTRACT:
Indazole compounds that modulate and/or inhibit cell proliferation, such as the activity of protein kinases are described. These compounds and pharmaceutical compositions containing them are capable of mediating, e.g., kinases-dependent diseases to modulate and/or inhibit unwanted cell proliferation. The invention is also directed to the therapeutic or prophylactic use of pharmaceutical compositions containing such compounds, and to methods of treating cancer as well as other disease states associated with unwanted angiogenesis and/or cellular proliferation, such as diabetic retinopathy, neovascular glaucoma, rheumatoid arthritis, and psoriasis, by administering effective amounts of such compounds.
REFERENCES:
“Some derivatives of 5-nitro and 5-amino-3-indazolecarboxylic acid”, Zh. Obshch. Khim., vol. 31, pp. 3255-3257, 1961.
Greene et. al., Protective Groups in Organic Synthesis, Wiley & Sons, Inc., p. 537.
Bleckman Ted Michael
Kephart Susan Elizabeth
Reich Siegfried Heinz
Romines William Henry
Wallace Michael B.
Agouron Pharmaceuticals , Inc.
Hsu Wendy L.
Richardson Peter C.
Robinson Binta
Zielinski Bryan C.
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