Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2006-03-29
2008-10-28
Bernhardt, Emily (Department: 1624)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
C514S255030, C514S252130, C514S253010, C540S575000, C544S360000, C544S379000, C544S398000, C544S399000, C544S400000, C544S402000
Reexamination Certificate
active
07442692
ABSTRACT:
A compound selected from those of formula (I):wherein:R3represents a hydrogen atom, and R1and R2together with the carbon atoms carrying them form a benzene, naphthalene or quinoline ring structure, each of the ring structures being optionally substituted,or R1represents a hydrogen atom, and R2and R3together with the carbon atoms carrying them form a benzene, naphthalene or quinoline ring structure, each of the ring structures being optionally substituted,n represents 1 or 2,—X— represents a group selected from —(CH2)m—O-Ak-, —(CH2)m—NR4-Ak-, —(CO)—NR4-Ak- and —(CH2)m—NR4-(CO)—,m represents an integer between 1 and 6 inclusive, Ak represents an optionally substituted alkylene chain, and R4represents a hydrogen atom or an alkyl group,Ar represents an aryl or heteroaryl group,its enantiomers, diasteroisomers, and addition salts thereof with a pharmaceutically acceptable acid.Medical products containing the same which are useful in the treatment of conditions requiring a serotonin reuptake inhibitor and/or NK1antagonist.
REFERENCES:
patent: 0745597 (1996-12-01), None
patent: 92/10192 (1992-06-01), None
patent: 2004/042351 (2004-05-01), None
Ryckmans et al. Bioorganic & Medicinal Chemistry Letters, vol. 12, pp. 3195-3198 (2002).
Preliminary Search Report: FR 0503071—Oct. 26, 2005.
De Nanteuil Guillaume
Gloanec Philippe
Gobert Alain
La Cour Clotilde Mannoury
Millan Mark
Bernhardt Emily
Hueschen and Sage
Les Laboratoires Servier
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