.increment..sup.16 unsaturated C.sub.17 heterocyclic steroids us

Details .increment..sup.16 unsaturated C.sub.17 heterocyclic steroids us .increment..sup.16 unsaturated C.sub.17 heterocyclic steroids us

1998-05-06

1999-10-12

Cook, Rebecca

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Cyclopentanohydrophenanthrene ring system doai

514880, A61K 3158

Patent

active

059655488

ABSTRACT:
The present invention relates to .DELTA..sup.16 unsaturated steroids which are useful as steroid C.sub.17-20 lyase inhibitors.

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Biggerstaff, et al., J. of Med. Chem. 12(1):1-5 (1969).
Doorenbos, et al., J. Org. Chem. 31(10):3193-3199 (1969).
Barton, et al., Tetrahedron 46(21):7587-7598 (1990).
Wiesner, et al., Helvetica Chimica Acta 65(7):2049-60 (1982).
P. Drasar, et al., Collection of Czechoslovak Chemical Comm.54(12), 3339-3347 (1989).
G. Rapi, et al., European J. of Med. Chem. Chemica Therapeutics 20(3) 277-282 (1985).
P. Drasar et al., J. of Chromatography 283, 396-400 (1984).

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