Increasing labeling efficiency by forming diagnostic agent in th

Details Increasing labeling efficiency by forming diagnostic agent in th Increasing labeling efficiency by forming diagnostic agent in th

1984-04-26

1987-02-24

Nucker, Christine M.

Drug, bio-affecting and body treating compositions

Radionuclide or intended radionuclide containing; adjuvant...

424 9, A61K 4300, A61K 4900

Patent

active

046456600

ABSTRACT:
A radioactive diagnostic agent having high labeling efficiency, prepared by bringing an aqueous solution of a radioactive metallic element contaminated with a non-radioactive metallic ions into contact with a non-radioactive carrier comprising a carrier substance having a chelate-forming property and optionally a physiologically active substance chemically bonded thereto, at least one of said aqueous solution and said non-radioactive carrier comprising at least one reductive material chosen from ascorbic acid and erythrobic acid, and their salts and esters.

REFERENCES:
patent: 4364920 (1982-12-01), Winchell
patent: 4425319 (1984-01-01), Yokoyama et al.
patent: 4455291 (1984-06-01), Tweedle
patent: 4489053 (1984-12-01), Azuma et al.
patent: 4504462 (1985-03-01), Van Duzee et al.
patent: 4510125 (1985-04-01), Grogg et al.

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