Increasing ionization efficiency in mass spectroscopy

Radiant energy – Ionic separation or analysis – Methods

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C250S281000, C250S42300F, C250S427000

Reexamination Certificate

active

07939797

ABSTRACT:
A mass spectrometry ionization method in which electrospray droplets or solid sample matrices are exposed to an ion beam thereby increasing the unbalanced charge of the analyte is provided. In another embodiment, a mass spectrometry ionization method in which ionization of the sample is achieved by directing an ion beam at a liquid or solid sample matrix containing analyte thereby ionizing and adding unbalanced charge to the analyte is provided.

REFERENCES:
patent: 5101105 (1992-03-01), Fenselau et al.
patent: 5589685 (1996-12-01), Jen Wu et al.
patent: 5750988 (1998-05-01), Apffel et al.
patent: 5873523 (1999-02-01), Gomez et al.
patent: 5907154 (1999-05-01), Shimomura
patent: 6147345 (2000-11-01), Willoughby
patent: 6218672 (2001-04-01), Alig
patent: 6541767 (2003-04-01), Kato
patent: 6621075 (2003-09-01), Hindsgaul et al.
patent: 6649907 (2003-11-01), Ebeling et al.
patent: 6660999 (2003-12-01), Bemish
patent: 6812459 (2004-11-01), Fischer et al.
patent: 7084396 (2006-08-01), Schneider
patent: 7462823 (2008-12-01), Schneider
patent: 2002/0040966 (2002-04-01), Bemish
patent: 2002/0125423 (2002-09-01), Ebeling et al.
patent: 2004/0089802 (2004-05-01), Kato
patent: 2006/0124847 (2006-06-01), Kato
patent: 60-194338 (1985-10-01), None
patent: 02-199761 (1990-08-01), None
patent: 06-213870 (1994-08-01), None
patent: 2001-174437 (2001-06-01), None
patent: WO02/078048 (2002-10-01), None
Smith, et al (“Quantitative Imaging and microlocalization of Boron-10 in Brain Tumors and Infiltrating Tumor Cells by SIMS Ion Microscopy: Relevance to Neutron Capture Therapy” Cancer Research, 61, 8179-8187, Nov. 15, 2001).
Jen Wu, et al (“Matrix-Enhanced Secondary Ion Mass Spectrometry: A Method for Molecular Analysis of Solid Surfaces” Anal. Chem. 68, 1996, pp. 873-882).
Supplementary European Search Report dated Oct. 23, 2007 from related EP application No. 03816566.8.
Takada, Yasuaki et al., “Atmospheric pressure chemical ionization interface for capillary electrophoresis/mass spectrometry”, Anal. Chem. 67(8):1474-6, Apr. 15, 1995.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Increasing ionization efficiency in mass spectroscopy does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Increasing ionization efficiency in mass spectroscopy, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Increasing ionization efficiency in mass spectroscopy will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-2704048

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.