Increasing cyclodextrin yields by the addition of various solute

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

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C08B 3716

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active

047482370

ABSTRACT:
The yield of cyclodextrins formed in the hydrolysis of starch catalyzed by a cyclodextrin glycosyltransferase can be substantially increased by the addition of certain water-soluble solutes. Alcohols containing 1 to 6 carbon atoms form one such class, with ethanol and isopropyl alcohol being especially effective. Where an immobilized cyclodextrin glycosyltransferase is used yields of beta-cyclodextrin can be increased from approximately 20% to almost 40% using 15% isopropyl alcohol in a thinned starch feedstock, with glucose production being increased by only about 25%.

REFERENCES:
patent: 2845417 (1958-07-01), Kesler et al.
J. Szejtli, Starch, 34, 379-85 (1982).
K. Horikoshi, Process Biochemistry, May 1979 (26-30).
M. Matzuzawa et al., Die Starke, 27, 410-13 (1975).

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