Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Separation or purification
Reexamination Certificate
2006-11-22
2009-06-09
Mertz, Prema (Department: 1646)
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Separation or purification
C530S417000, C530S418000, C530S419000
Reexamination Certificate
active
07544784
ABSTRACT:
The invention provides methods of increasing yields of desired conformation of proteins. In particular embodiments, the invention includes contacting preparations of a recombinant protein with a reduction/oxidation coupling reagent for a time sufficient to increase the relative proportion of a desired configurational isomer.
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McCoy Rebecca E.
Remmele, Jr. Richard L.
Sassenfeld Helmut M.
Fowler Kathleen
Immunex Corporation
Mertz Prema
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