Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues
Reexamination Certificate
2007-01-02
2007-01-02
O'Hara, Eileen B. (Department: 1646)
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
C530S412000, C530S413000, C530S417000, C530S202000, C514S012200, C435S325000, C435S069100, C435S069700, C536S023100, C536S023400, C536S023500
Reexamination Certificate
active
10080471
ABSTRACT:
The invention provides methods of increasing yields of desired conformation of proteins. In particular embodiments, the invention includes contacting preparations of a recombinant protein with a reduction/oxidation coupling reagent for a time sufficient to increase the relative proportion of a desired configurational isomer.
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McCoy Rebecca E.
Remmele, Jr. Richard L.
Sassenfeld Helmut M.
Fowler Kathleen
Immunex Corporation
O'Hara Eileen B.
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