Increased enantioselectivity of lipase catalyzed transesterifica

Details Increased enantioselectivity of lipase catalyzed transesterifica Increased enantioselectivity of lipase catalyzed transesterifica

1995-09-18

1997-06-17

Saucier, Sandra E.

Chemistry: molecular biology and microbiology

Process of utilizing an enzyme or micro-organism to destroy...

Resolution of optical isomers or purification of organic...

435135, 435155, C12P 4100

Patent

active

056396627

ABSTRACT:
Process for enhancement of enantioselectivity in the enzymatic separation of (R)- and (S)-enantiomers of an asymmetric alkynol, a lipase and in the presence of at least one vinyl ester, in which the acid component has at least 4 C atoms, an organic solvent and with the addition of water. Also disclosed is a process for enhancement of enantioselectivity in the enzymatic separation of (R)- and (S)-enantiomers of an alcohol with the aid of the abovementioned vinyl ester under addition of a second vinyl ester having at least 2 C atoms less in the alkyl chain than the vinyl ester used as esterifying agent.

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Patent Abstracts of Japan, C-911, Feb. 18, 1992, 16, No. 63: JP 3-259004.

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