Increased cell resistance to toxic organic substances

Chemistry: molecular biology and microbiology – Micro-organism – per se ; compositions thereof; proces of... – Bacteria or actinomycetales; media therefor

Reexamination Certificate

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C435S041000, C435S128000, C435S132000, C435S170000, C435S171000, C435S252700, C435S252900

Reexamination Certificate

active

06960465

ABSTRACT:
Recombinant microorganisms and related methods of use to enhance tolerance to toxic substances. In particular, such microorganisms and methods can be used to increase solvent production.

REFERENCES:
patent: 6156532 (2000-12-01), Kimura et al.
patent: 6159708 (2000-12-01), Sogo et al.
Pich, A., F. Narberhaus, and H. Bahl. 1990 Appl. Microbiol. Biotechnol. 33:697-704.
Walter, K.A., L.D. Mermelstein, and E.T. Papoutsakis. 1994 FEMS Microbiol. Lett. 123:335-342.
Kalbach, C.E., and Gatenby, A.A. 1993 Ezyme Microb. Technol. 15(9): 730-735.
Mizunoe, Y., Wai, S., Umene, K., Kokubo, T., Kawabata, S., and Yoshida, S. 1999 Microbiol. Immunol. 43(6):513-520.
Tomas, C., Welker, N., Papoutsakis, E. 2003 Appl. and Environ. Microbiol. 69(8): 4951-4965.
Aono, R., Improvement of Organic Solvent Tolerance Level ofEscherichia coliby Overexpression of Stress- Responsive Genes, Extremophiles, 1998, 2:239-248.
Asako, H., Nakajima, H., Kobayashi, K., Kobayaski, M., and Aono, R., Organic Solvent Tolerance and Antiobiotic Resistance Increased by Overexpression ofmarAinEscherichia coli, Applied and Environmental Microbiology, Apr. 1997, p. 1428-1433.
Bahl, H., Muller, H., Behrens, S., Joseph, H., and Narberhaus, F., Expression of Heat Shock Genes inClostridium acetobutylicum, FEMS Microbiology Reviews 17, 1995, p. 341-348.
Bahl, H., Chapter 11: Heat Shock Response and Onset of Solvent Formation inClostridium acetobutylicum, The Clostridia and Biotechnology, D.R. Woods, Editor, 1993, p. 247-259.
Bukau, B., and Walker, G. Cellular Defects Caused by Deletion of theEscherichia coli dnaKGene Indicate Roles for Heat Shock Protein in Normal Metabolism, Journal of Bacteriology, May 1989, p. 2337-2346.
Kieboom, J., Dennis, J., de Bont, J., and Zylstra, G., Identification and Molecular Characterization of an Efflux Pump Involved inPseudomonas putidaS12 Solvent Tolerance, The Journal of Biological Chemistry, Jan., 1998, vol. 273, No. 1, p. 85-91.
Li, X, Zhang, L., and Poole, K., Role of the Multidrug Efflux Systems ofPseudomonas aeruginosain Organic Solvent Tolerance, Journal of Bacteriology, Jun. 1998, p. 2987-2991.
Nishihara, K., Kanemori, M., Kitagawa, M., Yanagi, H., and Yura, T., Chaperone Coexpression Plasmids: Differential and Synergistic Roles of DnaK-DnaJ-GrpE and GroEL-GroES in Assisting Folding of an Allergen of Japanese Cedar Pollen, Cryj2, inEscherichia coli, Applied and Environmental Microbiology, May 1998, p. 1694-1699.
Pich., A, Narberhaus, F., and Bahl, H., Induction of Heat Shock Proteins During Initiation of Solvent Formation inClostridium acetobutylicum, Appl. Microbiol. Biotechnol. 1990, 33:697-704.
Volker, U., Mach, H., Schmid, R., and Hecker, M., Stress proteins and cross-protection by heat shock and salt stress inBacillus subtilis, Journal of General Microbiology, 1992, 138, 2125-2135.
White, D., Goldman, J., Demple, B., and Levy, S., Role of theacrABLocus in Organic Solvent Tolerance Mediated by Expression ofmarA, soxS, orrobAinEscherichia coli, Journal of Bacteriology, Oct. 1997, p. 6122-6126.
Wu, S., Ye, R., Wu, X, Ng, S., and Wong, S., Enhanced Secretory Production of a Single-Chain Antibody Fragment fromBacillus subtilisby Coproduction of Molecular Chaperones, Journal of Bacteriology, Jun. 1998, p. 2830-2835.
Soucaille, P., Joliff, G., Izard, A., and Goma, G., Butanol Tolerance and Autobacteriocin Production byClostridium acetobutylicum, Current Microbiology, vol. 14, 1987, p. 295-299.
Yura, T., and Nakahigashi, K., Regulation of the Heat-Shock Response, Current Opinion in Microbiology, 1999, 2:153-158.
Zuber, U., and Schumann, W., Circe, a Novel Heat Shock Element Involved in Regulation of Heat Shock OperondnaKofBacillus subtilis, Journal of Bacteriology, Mar. 1994, p. 1359-1363.
Mizunoe, Y., Wai, S., Umene, K., Kokubo, T., Kawabata, S., and Yoshida, S., Cloning, Sequencing, and Functional Expression inEscherichia coliof Chaperonin (groESL) Genes fromVibrio cholerae, Microbiol. Immunol., 1999, 43(6), p. 513-520.
Walter, K., Mermelstein, L., and Papoutsakis, E., Host-Plasmid Interactions in Recombinant Strains ofClostridium acetobutylicumATCC 824, FEMS Microbiology Letters 123, 1994, p. 335-342.
Kalbach, C., and Gatenby, A., Stable Expression Plasmid for High-Level Production of GroE Molecular Chaperones in Large-Scale Cultures, Enzyme Microb. Technol., 1993, vol. 15, p. 730-735.
Tomas, C., Welker, N., and Papoutsakis, E., Overexpression ofgroESLinClostridium acetobutylicumResults in Increased Solvent Production and Tolerance, Prolonged Metabolism, and Changes in the Cell's Transcriptional Program, Applied and Environmental Microbiology, Aug. 2003, p. 4951-4965.

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