Inclusion complexes of cyclodextrins by agglomeration

Details Inclusion complexes of cyclodextrins by agglomeration Inclusion complexes of cyclodextrins by agglomeration

1989-04-14

1991-12-03

Griffin, Ronald W.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

536103, 514778, 514974, 512 4, A61K 962, A61K 3170, B01J 1302

Patent

active

050700812

ABSTRACT:
A combined process is described in which inclusion complexes are formed from guest molecules and cyclodextrins during agglomeration of the cyclodextrins. Sufficient agitation in the presence of a small amount of water results in complex formation and bonding into strong agglomerates. The agglomerates are strong and stable and useful inter alia in foods (the guest molecules are flavors), pharmaceuticals (the guest molecules are drugs) and agriculture (the guest molecules are various agrochemicals).

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patent: 4916161 (1990-04-01), Patell
M. Kurozumi et al., "Inclusion Compounds of Non-Steroidal Antiinflammatory and Other Slightly Soluble Drugs with .alpha.-and .beta.-Cyclodextrins in Powdered Form", Chem. Pharm. Bull. 23 (12), 3062-3068 (1975).

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