Inactive variants of the human telomerase catalytic subunit

Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Transferase other than ribonuclease

Reexamination Certificate

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C530S350000, C514S012200, C424S094500, C536S023500

Reexamination Certificate

active

07091021

ABSTRACT:
The invention provides compositions and methods related to human telomerase reverse transcriptase (hTRT), the catalytic protein subunit of human telomerase. Catalytically active and inactive human telomerase reverse transcriptase variants comprising deletions or other mutations are provided.

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