Inactivation of viruses containing essential lipids

Details Inactivation of viruses containing essential lipids Inactivation of viruses containing essential lipids

1983-08-31

1986-04-08

Warden, Robert J.

Drug, bio-affecting and body treating compositions

Fermentate of unknown chemical structure

Having a known elemental analysis

260112B, 435238, 514 2, A61K 3514, C07G 700, C12N 706

Patent

active

045812314

ABSTRACT:
A method of inactivating a lipid virus in a protein carrier by contacting said virus for an abbreviated period of time and ambient temperature with a halohydrocarbon solvent or treating agent, preferably chloroform, in an amount of 5% v/v to 50% v/v. Preferred lipid viruses are Hepatitis B virus (HBV) and non-A, non-B Hepatitis (NANBH).

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Purcell, "The Hepatitis Viruses; An Overview and Historical Perspective", Viral Hepatitis, 1981 Franklin Institute Press.
Maramorosch et al., Methods in Virology, vol. 2, 1967.

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