Inactivation of human immunodeficiency virus (HIV) in protein-co

Details Inactivation of human immunodeficiency virus (HIV) in protein-co Inactivation of human immunodeficiency virus (HIV) in protein-co

1988-03-10

1989-12-12

Rosen, Sam

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

435236, 435238, 514 3, 514 6, A61K 3702

Patent

active

048867799

ABSTRACT:
A procedure for the inactivation of human immunodeficiency virus (HIV) in protein solutions as described, which process comprises addition of a phenol to a solution of this type, and allowing it to act. It is possible in this way, for example, to prepare products for human use which are free of any infectious HIV and thus do not transmit AIDS. Phenol is used at a low concentration and can be used at a ph of 3.5 to 4.5.

REFERENCES:
patent: 4188375 (1980-02-01), Straub
patent: 4711876 (1987-12-01), Catapano
patent: 4713240 (1987-12-01), Wilkins et al.
patent: 4746508 (1988-05-01), Carey et al.
Ferrari et al.-Chem. Abst., vol. 105 (1986), p. 57776y.
Eggensperger et al.-Chem. Abst., vol. 98 (1983), p. 59915d.
Avram et al., "Resistance of Bovine Leukosis Virus (BLV) to Various Physical and Chemical Agents," Lucrarile Institutului de Cercetari Veterinare si Biopreparate Pasteur, vol. 16, pp. 69-75 (1982).

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