Inactivated Mycolplasma hyopneumoniae and uses therefor

Details Inactivated Mycolplasma hyopneumoniae and uses therefor Inactivated Mycolplasma hyopneumoniae and uses therefor

1998-01-02

1999-10-19

Minnifield, Nita

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

4241841, 4242031, 4242341, 4242551, 4242531, 4242401, 424825, 435236, 4352351, 435243, 435245, 435237, A61K 3902, A61K 39116, A61K 39102, C12N 700

Patent

active

059685255

ABSTRACT:
The invention relates to a method for making an inactivated vaccine of Mycoplasma hyopneumoniae by inactivating the bacteria with Thimerosal. The resulting bacterin is mixed with an adjuvant of aluminum hydroxide and DEAE dextran and injected into pigs. The resulting bacterin and adjuvant mixture can also be mixed with other bacteria such as Bordetella and Pasteurella, for further adjuvant effect. Protective immunity against mycoplasmal pneumonia is elicited in swine using these vaccines.

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