Inactivated avian polyomavirus vaccine in psittacine birds

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Virus or component thereof

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4242791, 4242821, 424816, A61K 3912

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active

055230881

ABSTRACT:
The present invention provides a vaccine which is protective against avian polyomavirus infection in a bird which is classified as being a member of the Psittaciformes order which comprises an immunogenic amount of an inactivated avian polyomavirus in a pharmaceutically acceptable carrier. Also provided is an adjuvant suitable for use in a bird which is classified as being a member of the Psittaciformes order. Further provided is a composition which produces an anamnestic response against avian polyomavirus infection in a sensitized bird which is classified as being a member of the Psittaciformes order, which comprises an anamnestic response inducing amount of a recombinant protein (e.g., VP1 capsid protein) of avian polyomavirus in a pharmaceutically acceptable carrier. Methods are also provided for preventing avian polyomavirus infection in a bird, or in several different species of birds, classified as being a member of the Psittaciformes order, comprising administering a vaccine comprising an immunogenic amount of an inactivated avian polyomavirus and a pharmaceutically acceptable carrier.

REFERENCES:
Epstein et al, Clin Exp. Immunol. 63:485-490, 1986.
Chinnah et al, Vaccine 10(8) 551-557, 1992.
Della-Porta et al, Vet Microbiol, 4:197-208, 1979.
Niagro et al, Proc. Assoc. Avian Vet. 22-26, 1991.
Ritchie et al., "Polyomavirus Infections in Adult Psittacine Birds," J. Assoc. Avian Vet. 5:202-206 (1991).
Graham and Calnek, "Papovavirus Infection in Hand-Fed Parrots: Virus Isolation and Pathology," Avian Diseases 31:398-410 (1985).
Ritchie et al., "Avian Polyomavirus: An Overview," J. Assoc. Avian Vet. 5:147-153 (1991).
Stoll et al., "Molecular and biological characteristics of avian polyomaviruses: isolates from different species of birds indicate that avian polyomaviruses form a distinct subgenus within the polyomavirus genus," J. Gen. Virology 74:229-237 (1993).
Gaskin, J. M., "Adverse reactions to current pet bird vaccines," J. Assoc. Avian Vet. 5:12-14 (1991).
Sheets et al., "Studies of the effect of acemannan on retrovirus infections: Clinical stabilization of feline leukemia virus infected cats," Mol. Biother. 3:41-45 (1991).
Lehn and Muller, "Cloning and characterization of budgerigar fledgling disease virus (BFDV), an avian polyomavirus," Virology 151:362-370 (1986).
Niagro et al., "Use of polymerase chain reaction for detection of PBFD virus & BFD virus in suspect birds," Proc. Assoc. Avian Vet., Phoenix:25-37 (1990).
Phalen et al., "Polymerase chain reaction assay for avian polyomavirus," J. Clin. Microbiol. 29:1030-1037 (1991).
Fogleman et al., "Toxicologic Evaluation of Injectable Acemannan in the Mouse, Rat and Dog," Vet. Hum. Toxicol. 3:201-205 (Jun., 1992).
Harris et al., "Efficacy of acemannan in treatment of canine and feline spontaneous neoplasms," Mol. Biother. 3:207-213 (Dec. 1991).
Paige B. Garnett, D. V. M., "Immunostimulant Brings Positive Results in Studies," Veterinary Forum (Mar., 1993).
Peng et al., "Decreased mortality of Norman Murine Sarcoma in mice treated with the immunomodulator, Acemannan," Mol. Biother. 3:79-87 (Jun., 1991).
Rodriguez-Bigas et al., "Comparative Evaluation of Aloe Vera in the Management of Burn Wounds in Guinea Pigs," Plastic and Reconstructive Surgery 81(3):386-389 (Mar. 1988).
Swaim et al., "Effects of Topical Medications on the Healing of Open Pd Wounds in Dogs," Journal of the American Animal Hospital Association 28:499-502 (Nov./Dec. 1992).

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