In vivo use of water absorbent polymers

Details In vivo use of water absorbent polymers In vivo use of water absorbent polymers

2005-06-21

2005-06-21

Page, Thurman K. (Department: 1615)

Drug, bio-affecting and body treating compositions

Solid synthetic organic polymer as designated organic active...

Aftertreated polymer

Reexamination Certificate

active

06908609

ABSTRACT:
The subject invention is a method and material for removing fluid from the intestinal tract of a host and may be useful in treating animals or human patients suffering from fluid overload states. In one embodiment, the subject method involves ingesting an enterically coated non-systemic, non-toxic, non-digestible, water absorbing polymer which absorbs fluid while passing through the intestinal tract. The polymer is excreted in the feces wherein the polymer and absorbed fluid is removed from the body. Preferred polymers include super absorbent acrylic acid polymers, preferably provided in bead form. The polymers may include functional groups for selectively removing blood borne waste products, e.g. urea, from the G.I. tract.

REFERENCES:
patent: 2909462 (1959-10-01), Warfield et al.
patent: 3926891 (1975-12-01), Gross et al.
patent: 3935099 (1976-01-01), Weaver et al.
patent: 3997484 (1976-12-01), Weaver et al.
patent: 4076663 (1978-02-01), Masuda et al.
patent: 4090013 (1978-05-01), Ganslaw et al.
patent: 4093776 (1978-06-01), Aoki et al.
patent: 4143130 (1979-03-01), Imondi et al.
patent: 4190562 (1980-02-01), Westerman
patent: 4286082 (1981-08-01), Tsubakimoto et al.
patent: 4340706 (1982-07-01), Obayashi et al.
patent: 4446261 (1984-05-01), Yamasaki et al.
patent: 4459396 (1984-07-01), Yamasaki et al.
patent: 4470975 (1984-09-01), Berger et al.
patent: 4605701 (1986-08-01), Harada et al.
patent: 4683274 (1987-07-01), Nakamura et al.
patent: 4708997 (1987-11-01), Stanley, Jr. et al.
patent: 4833198 (1989-05-01), Stanley, Jr. et al.
patent: 4857610 (1989-08-01), Chmelir et al.
patent: 4985518 (1991-01-01), Alexander et al.
patent: 5004603 (1991-04-01), Thompson
patent: 5051253 (1991-09-01), Lloyd-Jones et al.
patent: 5145906 (1992-09-01), Chambers et al.
patent: 5407682 (1995-04-01), Schacht et al.
patent: 5487888 (1996-01-01), Mandeville, III et al.
patent: 5607669 (1997-03-01), Mandeville, III et al.
patent: 5618530 (1997-04-01), Mandeville, III et al.
patent: 5629377 (1997-05-01), Burgert et al.
patent: 5679717 (1997-10-01), Mandeville, III et al.
patent: 5693675 (1997-12-01), Mandeville, III et al.
patent: 5702696 (1997-12-01), Mandeville, III et al.
patent: 6132706 (2000-10-01), Hider et al.
patent: 6204243 (2001-03-01), Posanski
patent: 0077956 (1982-08-01), None
patent: 0077956 (1983-04-01), None
patent: 314825 (1993-02-01), None
patent: H 10-130154 (1988-05-01), None
patent: H 10-59851 (1998-03-01), None
patent: WO 85/01207 (1985-03-01), None
patent: WO 95/05856 (1995-03-01), None
patent: WO 95/35100 (1995-12-01), None
patent: WO 96/10995 (1996-04-01), None
patent: WO 98/17707 (1998-04-01), None
patent: WO 00/50096 (2000-08-01), None
Giordano et al, “An Improved Oxystarch in the Treatment of Renal Failure” Artif. Organs, Proc Semin, 1977 Meeting Date 1976, pp. 327-332 Chem. Abstract No. 88:69294 (1998)—Abstract only.
Mohan, T. J. et al, “Evaluation of Silicone Oil and Carboxymethylcellulose (Acid) As Enteic Coating for Tablets” Drug Standards, vol. 24(1), 1956, pp. 18-22.
Imondi, A.R. et al, “Gastrointestinal Sorbents for the Treatment of Uremia” Ann. Nutr. Metabol., vol. 25, 1981, pp. 311-319.
Murthy et al, “In Vitro Release Characteristsc of Hard Shell Capsule Products Coated with Aqueous- and Organic-Based Enteric Polymers”J. Biomater.Appl., vol. 3(1), 1998, pp. 52-79.
“Nomenclature and Chemistry,”BFGoodrich Pharmaceutical Division,Bulletin 3, Apr. 1995, pp. 1-5.
Porter et al, “The Permeability of Enteric Coaings and the Dissolution Rates of Coated Tablets” J. Pharm. Pharmacol., vol. 34(1) (1982) pp. 5-8.
“Polycarbophil,” Product Information from website ofClinical Pharmacology,Gold Standard Multimedia, 2000, 2 pages.
Saffran, et al., “A New Approach to the Oral Administration of Insulin and Other Peptide Durgs”Science,vol. 235, 1986, pp. 1081-1084.
Thoma et al, “Influence of Aqueous Coatings on the Stability of Enteric Coated Pellets and Tablets” Eur. J. Pharm. Biopharm., vol. 47 (1), 1999 pp 39-50.
Yatzidis et al, “Newer Oral Sorbents in Uremia” Clin. Nephrol, vol. 11(2), 1979, pp. 105-106.
Yatzidis, “Preliminary Studies with Locust Bean Gum: A New Sorbent With Great Potential”, Kidney Int. Supplement, vol. 13(8), 1978, pp. 150-152.
Zeig et al, “Potential For Oral Sorbent Treatment of Uremia”, Sorbents Their Clinical Application, Academic, New York, NY, 1980, pp. 275-294.
Buchholz, F.L. and Burgert, J.H. “Synthesis and Applications of Superabsorbent Polymers,” Nov. 1996, pp. 1-11.
Cheng et al, “Development of an Azoplymer Based Colonic Release Capsule for Delivering Proteins/Macromolecules” Methods and Findings in Experimental and Clinical Pharmacology, vol. 16(4), May 1994, pp. 271-278—Abstract only.
Friedman, Eli A., “Oral Sorbents as Adjunctive Treatment in Uremia” Replacement Renal Funct. Dial., Nijhoff, The Hague, Netherlands, 1978, pp. 232-243.

Affiliated with

Also associated with

Rating

In vivo use of water absorbent polymers does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with In vivo use of water absorbent polymers, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and In vivo use of water absorbent polymers will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3481585