In vivo treatment of mycobacterial infections with 6-cyclo octyl

Details In vivo treatment of mycobacterial infections with 6-cyclo octyl In vivo treatment of mycobacterial infections with 6-cyclo octyl

1986-07-30

1990-10-16

Goldberg, Jerome D.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

A61K 3147

Patent

active

049635654

ABSTRACT:
6-cyclo-octylamino-5,8-quinoline quinone, a Vitamin K analogue, shows surprising efficacy as an in vivo therapeutic agent for treatment of tuberculosis and leprosy. Mycobacteria species, intracellulare, tuberculosis, and leprae are inhibited following administration of the compound in any form.

REFERENCES:
patent: 4492704 (1985-01-01), Fleisch et al.
Chemical Abstracts 76:108223h (1972).
Chemical Abstracts 89:209669g (1978).
Tubercle 62 (1981) 37-41.
Gangadharam, et al., Am. Rev. Resp. Dis. 118: 467-473 (1978).

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